Latest #myday Posts
- Telomeres and ageing. .
Telomeres are the "caps" at the ends of eukaryotic chromosomes (shown in green). These hexanucleotide repeats run for an average 5 - 15 kb in humans and play a crucial role in genome stability. Yet these protective repeats shorten with each somatic cell division, and this is one of the leading hypotheses as to why we age. .
One of the most striking pieces of evidence for telomeric length and ageing is that mutations in genes responsible for telomere maintenance or telomerase lead to disorders that display an onset of premature ageing symptoms, like Progeria, and these individuals have much shorter lifespans than those unaffected by these mutations. Telomeric shortening can have both positive and negative effects: cancer cell proliferation can be halted due to a breakdown in telomeres, however most phenotypic displays of ageing, eg. collagen loss in tissue, is also a result of shortening telomeres. .
Interestingly, the standard lab mouse isn't a great model for studying telomeres and ageing: mice have telomere lengths several times that of what humans have, and their average lifespan ends before any critical telomere shortening is observed. Additionally, telomerase knockout mice are fine for several generations before issues emerge. Thus, the vertebrate model organism for telomeric length and ageing is actually the zebrafish, whose telomere length matches our own (5 - 15kb) and whose telomerase protein shares a number of conserved structural motifs with that in humans. .
Though therapeutics have yet to emerge for halting or reversing telomere shortening, we do know a number of things that contribute to the speed at which they shorten, such as UV radiation, stress, tissue damage, etc. So sunscreen and meditation may hold some effect over the ageing process! .
Img from stanford.edu
#science #stem #biology #biochemistry #genetics #molecularbiology #microbiology #womeninstem #womeninscience #lifesciences #sciencestudent #myday #instascience #research #laboratory #lab #lablife #scientist #telomeres #ageing
- My few pics from my very busy day....
Picking flowers with the princess, snuggles with the little man, OT with Will, and Coopers “fat Christmas tree” (as he described it) potato head playdough person. Lots of fun
#adayinthelife #photos #myday #memoriesforever
- É hoje 🎂🎈🎊🍾, mais um ano de vida , agradecida a Deus por me permitir , por guiar meus caminhos , por ser minha luz , meu abrigo e por trazer para minha vida pessoas tão especiais ! Quero levar minha vida com este sorriso nos lábios independente do que aconteça , com minha paz interior , minha serenidade ( nem sempre kkkk ) , meu caráter e minha verdade . Segue o baile partiu para comemorar 🍾🍾🍾🍾🍾 #happybirhtday #myday #happy #life #thanksgood🙏 😍
- 비싼 초기비용 내고
큰 맘먹고 시작 했는데
이런 노가다 시키는
멘토가 아직도 있다니
다 시간 낭비고
효과 없어요!! 성공하는 지름길
저 쑤영이 안내 해드릴게요
- BRIANNNNNNNNNNN!!!!!!! yes. He's soft. So soft. I've been feeling off yeeHee. Some people are just straight up annoying. Appreciate the people around you,,,,be nice to them. This edit isn't really good but- ayeeeeee ye....do you ever just remember san hitting the whoa, sticking his tongue out? Ye same. BRAIN BOI LOOK AT HIM ITEIEJYSKYSKGS stan day6 my doods♥️♥️♥️
Top #myday Posts
- Skills include:
1. Pretending I have a life
2. Going to bed at 9pm
3. Seeing how much I can procrastinate and still pass my exams
- ‘s ᴘᴏsᴛ ; what a coincidence, it’s literally father’s day LOL 😭